Local Ca2+ Release from Internal Stores Controls Exocytosis in Pituitary Gonadotrophs
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چکیده
منابع مشابه
Local Ca2+ Release from Internal Stores Controls Exocytosis in Pituitary Gonadotrophs
Exocytosis and the cell-averaged cytosolic [Ca2+], [Ca2+]i, were tracked in single gonadotrophs. Cells released 100 granules/s at 1 microM = [Ca2+]i when gonadotropin-releasing hormone (GnRH) activated IP3-mediated Ca2+ release from internal stores, but only 1 granule/s when [Ca2+]i was raised uniformly to 1 microM by other means. Strong exocytosis was then seen only at higher [Ca2+]i (half-max...
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ژورنال
عنوان ژورنال: Neuron
سال: 1997
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(01)80051-9